Study on the relationship of depression, anxiety, lifestyle and eating habits with the severity of reflux esophagitis

Abstract Background The etiology of reflux esophagitis (RE) is multi-factorial. This study analyzed the relationship depression, anxiety, lifestyle and eating habits with RE its severity further explored impact anxiety depression on patients’ symptoms quality life. Methods From September 2016 to February 2018, a total 689 subjects at Xuanwu Hospital Capital Medical University participated in this survey. They were divided into group (patients diagnosed gastroscopy, n = 361) control (healthy individuals without heartburn, regurgitation other gastrointestinal symptoms, 328). survey included general demographic information, habits, comorbidities, current medications, gastroesophageal disease (GERD) questionnaire (GerdQ), Patient Health Questionnaire-9 scale General Anxiety Disorder-7 scale. Results mean age sex ratio two groups similar. Multivariate logistic regression analysis identified following factors as related onset ( p < 0.05): low education level; drinking strong tea; preferences for sweets, noodles acidic foods; sleeping pillow; overeating; short interval between dinner sleep; anxiety; depression; constipation; history hypertension; use oral calcium channel blockers. Ordinal revealed positive correlation pillow 0.025). Depression had (r s 0.375, 0.001) life 0.306, 0.001), whereas showed no such association. Conclusions Many correlated RE. Notably, was positively severity,